翻訳と辞書
Words near each other
・ Cyclidia rectificata
・ Cyclidia sericea
・ Cyclidia substigmaria
・ Cyclidia tetraspota
・ Cyclidiinae
・ Cyclin
・ Cyclin A
・ Cyclin A1
・ Cyclin A2
・ Cyclin B
・ Cyclin B1
・ Cyclin B2
・ Cyclin D
・ Cyclin D/Cdk4
・ Cyclin D1
Cyclin D2
・ Cyclin D3
・ Cyclin E
・ Cyclin E1
・ Cyclin E2
・ Cyclin H
・ Cyclin K
・ Cyclin O
・ Cyclin T1
・ Cyclin T2
・ Cyclin-dependent kinase
・ Cyclin-dependent kinase 1
・ Cyclin-dependent kinase 10
・ Cyclin-dependent kinase 2
・ Cyclin-dependent kinase 3


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Cyclin D2 : ウィキペディア英語版
Cyclin D2

G1/S-specific cyclin-D2 is a protein that in humans is encoded by the ''CCND2'' gene.
== Function ==

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of cyclin-dependent kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=894 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Cyclin D2」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.